3,4-Dihydro-2H-1,3-benzoxazines and their oxo-derivatives –Chemistry and bioactivities

Authors

  • Nabaweya Abd Elsalam Sharaf Eldin Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, El Giesh street, 31527, Tanta, Egypt https://orcid.org/0000-0001-5596-5561

DOI:

https://doi.org/10.2298/JSC180530001S

Keywords:

1,3-benzoxazines, synthesis, biological activities

Abstract

3,4-Dihydro-2H-1,3-benzoxazines derivatives are a significant class of heterocycles with particular awareness due to their remarkable biological activities in humans, plants and animals, and also their natural occurrence. Alt­er­ation in the benzoxazine skeleton and their comparative chemical simplicity and accessibility, make these compounds suitable sources of other bioactive compounds, resulting in the discovery of a wide set of these compounds that have broad biological activity, such as antifungal, antibacterial, anti-HIV, anti­cancer, anticonvulsant, anti-inflammatory, etc. Subsequently, this review gives herein a brief overview of the chemistry and bioactivities of derivatives of 3,4-
-dihydro-2H-1,3-benzoxazine monomers and their oxo-derivatives.

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Graphical Abstract

Published

2021-03-22

How to Cite

[1]
N. A. E. Sharaf Eldin, “3,4-Dihydro-2H-1,3-benzoxazines and their oxo-derivatives –Chemistry and bioactivities”, J. Serb. Chem. Soc., vol. 86, no. 3, pp. 213-246, Mar. 2021.

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