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/Author (Pantovic-Pavlovic, Marijana and Pavlovic, Miroslav and Kovacina, Jovanka and Stanojevic, Boris and Stevanovic, Jasmina and Panic, Vladimir and Ignjatovic, Nenad)
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/Title ({Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition})
/bibtex#2FDOI (10.2298/jsc210211024p)
/bibtex#2FPUBLISHER (Serbian Chemical Society)
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/Keywords (amorphous calcium phosphate,chitosan oligolactate,colorimetric test with tetrazolium salts,cytotoxicity,dye exclusion test)
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/Subject (Cytotoxicity of amorphous calcium phosphate \(ACP\) and chitosan lactate \(ChOL\) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line is elucidated. ACP/TiO2 and ACP/TiO2/ChOL are deposited onto Ti by novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells eposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. The findings show that there is improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for the applications in medicine and stomatology.)
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Cytotoxicity of amorphous calcium phosphate (ACP) and chitosan lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line is elucidated. ACP/TiO2 and ACP/TiO2/ChOL are deposited onto Ti by novel in situ anodization/anaphoretic process at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells eposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. The findings show that there is improved cell proliferation, differentiation and cell viability in the ChOL-containing sample, which makes ACP/TiO2/ChOL coating a good candidate for the applications in medicine and stomatology.
Marijana Pantovic-Pavlovic
Miroslav Pavlovic
Jovanka Kovacina
Boris Stanojevic
Jasmina Stevanovic
Vladimir Panic
Nenad Ignjatovic
bibtex/citationkey/Pantovic-Pavlovic2021
bibtex/file/:D\:/OneDrive/Mendeley Desktop/Pantovic-Pavlovic et al. - 2021 - Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by.pdf:pdf;:02_10372_5442.pdf:PDF
bibtex/issn/0352-5139
bibtex/journal/J. Serb. Chem. Soc.
bibtex/month/jun
bibtex/number/06
bibtex/pages/555--559
bibtex/url/https://www.shd-pub.org.rs/index.php/JSCS/article/view/10372
bibtex/volume/86
10.2298/jsc210211024p
amorphous calcium phosphate
chitosan oligolactate
colorimetric test with tetrazolium salts
cytotoxicity
dye exclusion test
Serbian Chemical Society
{Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition}
2021-06
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