Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition Note

Main Article Content

Marijana R. Pantović Pavlović
Miroslav M. Pavlović
https://orcid.org/0000-0003-3754-4143
Jovanka N. Kovačina
https://orcid.org/0000-0002-3494-9180
Boris P. Stanojević
https://orcid.org/0000-0002-6940-9328
Jasmina S. Stevanović
Vladimir V. Panić
https://orcid.org/0000-0002-8358-7956
Nenad L. Ignjatović
https://orcid.org/0000-0002-5749-094X

Abstract

The cytotoxicity of amorphous calcium phosphate (ACP) and chito­san lactate (ChOL) multifunctional and hybrid composite coatings on MRC-5 human lung fibroblast cell line was elucidated. ACP/TiO2 and ACP/TiO2/
/ChOL were deposited onto Ti by a novel in situ anodization/anaphoretic pro­cess at constant voltage. Cytotoxicity tests showed that there was no significant decrease in the survival of healthy MRC-5 cells exposed to composite samples without chitosan lactate, while there was an increase in the number of viable cells in the sample containing ChOL. These findings show that there was imp­roved cell proliferation, differentiation and cell viability in the ChOL-con­tain­ing sample, which makes ACP/TiO2/ChOL coating a good candidate for applications in medicine and stomatology.

Article Details

How to Cite
[1]
M. Pantović Pavlović, “Cytotoxicity of amorphous calcium phosphate multifunctional composite coatings on titanium obtained by in situ anodization/anaphoretic deposition: Note”, J. Serb. Chem. Soc., vol. 86, no. 6, pp. 555-559, Jun. 2021.
Section
Biochemistry & Biotechnology

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