Comparative study between homemade and commercial hawthorn (Crataegus spp.) extracts regarding their phenolic profile and antioxidant activity Scientific paper

Main Article Content

Nemanja Živanović
https://orcid.org/0000-0001-7839-2815
Nataša Simin
https://orcid.org/0000-0002-3837-453X
Marija Lesjak
https://orcid.org/0000-0001-9764-9903
Dejan Orčić
https://orcid.org/0000-0003-3474-1723
Neda Mimica-Dukić
https://orcid.org/0000-0002-8294-6881
Emilija Svirčev
https://orcid.org/0000-0002-9933-4021

Abstract

Crataegus species (hawthorn) have been commonly used in tradit­ional medicine, especially for the treatment of congestive heart failure. Many studies confirmed that they are rich in polyphenols, thus exhibiting strong antioxidant activity, which contribute to the beneficial effects of hawthorn on the cardiovascular system. In the market, there are many herbal medicinal pro­ducts based on hawthorn, which consumption as adjuvant therapy in heart-rel­ated issues is supported by European Medicines Agency. Since there is a global trend of making homemade herbal preparations, this study aimed to compare whether there is a difference in polyphenol profile and antioxidant potential between homemade and commercial ethanol extracts of hawthorn. Polyphenol profile was evaluated by determination of total phenolic and flavonoid cont­ents, and by quantitative analysis of selected polyphenols by liquid chromato­graphy–mass spectrometry/mass spectrometry. Antioxidant potential was exam­ined by 2,2-diphenyl-1-picrylhydrazyl, ferric ion reducing antioxidant power and lipid peroxidation inhibition assays. The results of this study suggest that homemade ethanol extracts of hawthorn flowers, leaves and fruits are just as good source of polyphenols and antioxidants as commercial ones, and their utilization should be supported. Furthermore, hawthorn extracts made of leaves and flowers are better source of bioactive polyphenols and have higher anti­oxidant activity compared with the same of fruits, regardless of the method of preparation.

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How to Cite
[1]
N. Živanović, N. Simin, M. Lesjak, D. . Orčić, N. . Mimica-Dukić, and E. . Svirčev, “Comparative study between homemade and commercial hawthorn (Crataegus spp.) extracts regarding their phenolic profile and antioxidant activity: Scientific paper”, J. Serb. Chem. Soc., vol. 89, no. 5, pp. 603–616, May 2024.
Section
15 years of Professor Emeritus UNS
Author Biographies

Nemanja Živanović, University of Novi Sad, Faculty of Sciences, Novi Sad, Serbia

Department for Chemistry, Biochemistry, and Environmental Protection

Marija Lesjak, University of Novi Sad, Faculty of Sciences, Novi Sad, Serbia

Department for Chemistry, Biochemistry, and Environmental Protection

Dejan Orčić, University of Novi Sad, Faculty of Sciences, Novi Sad, Serbia

Department for Chemistry, Biochemistry, and Environmental Protection

Neda Mimica-Dukić, University of Novi Sad, Faculty of Sciences, Novi Sad, Serbia

Department of Chemistry, Biochemistry and Enviromental Protection

Emilija Svirčev, University of Novi Sad, Faculty of Sciences, Novi Sad, Serbia

Department of Chemistry, Biochemistry and Enviromental Protection

Funding data

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