Synthesis and antimicrobial activity of new 3,5-diarylidene-4-piperidone derivatives

Main Article Content

Kulathooran Singaram
Dhamodaran Marimuthu
Selvakumar Baskaran
Venkataraman Ramaswamy

Abstract

Three series of heteroaromatic analogs (twenty seven compounds) with monoketone linkers have been synthesized and evaluated for their antimicrobial activity against six microbial strains. Among them, 3,5-dibenzylidene-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)piperidin-4-one 5e showed best antifungal activity against Aspergillus niger and Aspergillus fumigatus. Structural elucidation of the synthesized compounds was determined on the basis of various spectroscopic methods.

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How to Cite
[1]
K. Singaram, D. Marimuthu, S. Baskaran, and V. Ramaswamy, “Synthesis and antimicrobial activity of new 3,5-diarylidene-4-piperidone derivatives”, J. Serb. Chem. Soc., vol. 81, no. 8, pp. 859–870, Sep. 2016.
Section
Organic Chemistry
Author Biographies

Kulathooran Singaram, Research & Development Centre, Bharathiar University, Coimbatore-641046

Research scholar, Department of Chemistry

Dhamodaran Marimuthu, Department of Chemistry, Perunthalaivar Kamarajar Institute of Engineering and Technology, Karaikal-609603

Professor, Head of the Department, Department of Chemistry

Selvakumar Baskaran, Department of Chemistry, PG and Research Centre, Sriparamakalyani College, Alwarkurichi 627412

Research Scientist, Department of Chemistry

Venkataraman Ramaswamy, Department of Chemistry, PG and Research Centre, Sriparamakalyani College, Alwarkurichi 627412

Professor, Department of Chemistry

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