Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria

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Sawsen Bourezzane
Hamada Haba
http://orcid.org/0000-0002-7979-5007
Christophe Long
http://orcid.org/0000-0002-7677-7700
Mohammed Benkhaled
http://orcid.org/0000-0002-3209-0691

Abstract

This paper reports a phytochemical study of the aerial parts of Astra­galus monspessulanus L. growing in Algeria. It deals with the isolation and structure elucidation of 13 known compounds. From the n-butanol extract, seven flavonoids 17, two saponins and one lignan were isolated. In addition, two phytosterols and one triterpenoid were isolated from the ethyl acetate ext­ract. The structures of all the isolated products were determined by using 1D and 2D-NMR techniques, measurement of optical rotation, mass spectrometry ESI-MS and by comparison with literature data. Furthermore, the antioxidant activity of the n-butanol extract of the aerial parts of Astragalus mon­spes­sulanus L. was investigated using the DPPH radical scavenging and ferrous ion chelating assays. The n-butanol extract showed low (EC50 = 2.09±0.434 mg mL-1) to moderate (IC50 = 63.60±0.01 μg mL-1) antioxidant activities dep­ending on the test method.

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How to Cite
[1]
S. Bourezzane, H. Haba, C. Long, and M. Benkhaled, “Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria”, J. Serb. Chem. Soc., vol. 83, no. 1, pp. 31–38, Feb. 2018.
Section
Biochemistry & Biotechnology

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