Signal amplification for sumatriptan sensing based on polymeric surface decorated with Cu nanoparticles

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Ghasem Karim-Nezhad
Samane Khanaliloo
Zeynab Khorablou
Parisa Seyed Dorraji

Abstract

A new nanocomposite (Cu NPs/poly melamine) was deposited on glassy carbon electrode by cyclic voltammetry. Uniform deposition of the nanocomposite was observed by field emission scanning electron microscopy. The electron transfer characteristics of sumatriptan (SUM), was greatly improved on the modified electrode. The prepared electrode was used for sensitive determination of SUM by differential pulse voltammetry. Linear calibration curve was obtained in the concentration ranges of 0.08 - 0.58 and 0.58 6.5 μM, and detection limit of 0.025 µM. The proposed method was evaluated by determination of SUM in human biological fluids such as urine and blood plasma with satisfactory results (recovery > 99 %).

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How to Cite
[1]
G. Karim-Nezhad, S. Khanaliloo, Z. Khorablou, and P. Seyed Dorraji, “Signal amplification for sumatriptan sensing based on polymeric surface decorated with Cu nanoparticles”, J. Serb. Chem. Soc., vol. 83, no. 4, pp. 449–462, Apr. 2018.
Section
Electrochemistry

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