Facile synthesis and antifungal activity of dithiocarbamate derivatives bearing an amide moiety

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Yu-Wen Li
Shu-Tao Li

Abstract

Two series of novel dithiocarbamate derivatives bearing an amide moiety, 3a–3i and 4a–4i, were synthesized by a facile method, and the structures of the derivatives were confirmed by elemental analysis and 1H-NMR, 13C-NMR and high-resolution mass spectrometry (HRMS). Their antifungal activity against five phytopathogenic fungi were evaluated, and the results showed that most of the target compounds displayed low antifungal activity in vitro against Gibberella zeae, Cytospora sp., Collectotrichum gloeosporioides, Alternaria solani, and Fusarium solani at a concentration of 100 mg L-1. However, two compound, 4f and 4g, exhibited significant activity against A. solani and C. gloeosporioides, respectively.

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How to Cite
[1]
Y.-W. Li and S.-T. Li, “Facile synthesis and antifungal activity of dithiocarbamate derivatives bearing an amide moiety”, J. Serb. Chem. Soc., vol. 80, no. 11, pp. 1367–1374, Dec. 2015.
Section
Organic Chemistry