Electrocatalytic multicomponent assembling of aminouracils, aldehydes and malononitrile: An efficient approach to 7-amino-pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives
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Abstract
The electrocatalytic multicomponent transformation of 6-aminouracils, aromatic aldehydes and malononitrile in ethanol in an undivided cell in the presence of potassium bromide as an electrolyte leads to 7-amino-pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives in short reaction times (8–20 min) and in good to high yields (70–86 %).
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[1]
R. Kazemi-Rad, J. Azizan, and H. Kefayati, “Electrocatalytic multicomponent assembling of aminouracils, aldehydes and malononitrile: An efficient approach to 7-amino-pyrido[2,3-d]pyrimidine-6-carbonitrile derivatives”, J. Serb. Chem. Soc., vol. 81, no. 1, pp. 29–34, Feb. 2016.
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Organic Chemistry
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