Synthesis of two novel C-19 analogues of (±)-alstoscholarisine A (Short Communication)

Filip Bihelovic, Zorana Ferjancic, Zlatko Joncev


Two new analogues of alstoscholarisine A, containing a phenyl or butyl
substituent at the C-19 position, have been prepared in racemic form from the
known skatole derivative. The syntheses of these compounds were accomplished in
13 steps, with a late-stage formation of the C-19 stereocenter. These derivatives are expected to have significantly changed biological


аlkaloids; neuronal stem cells; Alstonia scholaris.


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