Biodegradation of a mixture of benzophenone, benzophenone-3, caffeine and carbamazepine in a laboratory test filter

Minja Bogunović, Varja Knežević, Jelica Simeunović, Ivana Teodorović, Ivana Ivančev-Tumbas

Abstract


The biodegradation of a mixture of four pharmaceutical and personal care products (PPCPs) (benzophenone (BP), benzophenone-3 (BP-3), caffeine (CF) and carbamazepine (CBZ)) was studied in a laboratory test filter. The column was filled with inert material to exclude adsorption processes and to enable the development of the biofilm, while river water was recirculated. High removal for BP, BP-3 and CF was observed from the beginning of the experiment at initial concentration of 20 µg L-1 (90-99 %). In the case of CBZ analytical difficulties were experienced. Efficacy of biodegradation reflected as a change of the overall toxicity of initial mixture of selected PPCPs vs. toxicity of samples undergone different biodegradation phases was assessed with two standard laboratory tests with apical endpoint - acute toxicity test with Daphnia magna (immobilisation) and bioluminescence inhibition with Vibrio fisheri. Toxicity tests showed the substantial reduction of overall mixture toxicity in a laboratory test filter. The residual toxicity to D. magna might be attributed to undetected transformation products.


Keywords


PPCPs mixture; toxicity; surface water

References


K. Kümmerer, J. Environ. Manage. 90 (2009) 2354

T.A. Ternes, M. Meisenheimer, D. McDowell, F. Sacher, H.J. Brauch, B. Haist-Guide, Environ. Sci. Technol. 36 (2002) 3855

K. Kotnik, T. Kosjek, B. Zegura, M. Filipi, E. Heath, Chem. 147 (2016) 114

A. Careghini, A. Filippo Mastorgio, S. Saponaro, E. Sezenna, Environ. Sci. Pollut. Res. 22 (2015) 5711

R. Loos, B. Gawlik Manfred, G. Locoro, E. Rimaviciute, S. Contini, G. Bidoglio, Environ. Pollut. 157 (2009) 561

M. König, B. Escher, P. Neale, M. Krauss, K. Hilscherová, J. Novák, I. Teodorović, T. Schulze, S. Seidensticker, MAK. Hashmi, J. Ahlheim, W. Brack, Environ. Pollut., B 220 (2017) 1220

E.N. Evgenidou, I.K. Konstantinou, D.A. Lambropoulou, Sci. Total Environ. 505 (2015) 905

B. Petrie, R. Barden, B. Kasprzyk-Hordern Water Res. 72 (2015) 3

M. Macova, B.I. Escher, J. Reungoat, S. Carswell, K.L. Chue, J. Keller, J.F. Mueller, Water Res. 44 (2010) 477

B. Escher, K. Fenner, Environ. Sci. Technol. 45 (2011) 3835

I. Liška, F. Wagner, M. Sengl, K. Deutsch, J. Slobodník, Joint Danube Survey 3 - A Comprehensive Analysis of Danube Water Quality, Final Scientific Report, International Commission for the Protection of the Danube River, Vienna, Austria, 2015, p. 335

E. Donner, T. Kosjek, S. Qualmann, K.O. Kusk, E. Heath, D.M. Revitt, A. Ledin, H.R. Andersen, Sci. Total Environ. 443 (2013) 870

S. Kim, K. Choi, Environ. Int. 70 (2014)

O. Takita, T. Tanaka, T. Ooi, S. Kinoshita, L.T.T. Ai, T. L. Thuoc, Osaka University Knowledge Archive, 2005, p. 185

D.Y. Chen, X.F. Guo, W. Hong, H.S. Zhang. Water. Sci. Technol. 72 (2015) 503

M. Cleuvers, Toxicol. Lett. 142 (2003) 185

H. Sontheimer, DVGW-Schriftenreihe Wasser 60 (1988) 27

S. Bertelkamp, J. Reungoat, E.R. Cornelissen, N. Singhal, J. Reynisson, A.J. Cabo, J.P. van der Hoek, A.R.D. Verliefde, Water Res. 52 (2014) 231

H. Börnick, Aromatic amines in the River Elbe-Development of analytical method and investigation into the behaviour during drinking water treatment, University of Technology, Dresden, 1998, pp. 23–49

W. Eckhard, T. Grischek, H. Börnick, P. Eppinger, J. Hydrol. 266 (2002) 259

M. D'Alessio, B. Yoneyama, C. Ray, Sci. Total Environ. 505 (2015) 615

B.S. Trinh, B. Reid, K. Hiscock, SpringerPlus 5 (2016) 1842

S.K. Maeng, K. Sharma, D.T. Abel Chol, A. Magic Knezev, A. L. Gary, Water Res. 45 (2011) 4722

A. S. Snayder, C. E. Wert, L. Hongxia, P. Westerhoff, Y. Yoon, AWWA Research Foundation, 2007, p. 195

National Center for Biotechnology Information. PubChem Compound Database; CID=3102, https://pubchem.ncbi.nlm.nih.gov/compound/3102 (accessed Dec 2, 2016)

National Center for Biotechnology Information. PubChem Compound Database; CID=4632, https://pubchem.ncbi.nlm.nih.gov/compound/4632 (accessed Dec 2, 2016)

National Center for Biotechnology Information. PubChem Compound Database; CID=2554, https://pubchem.ncbi.nlm.nih.gov/compound/2554 (accessed Dec 2, 2016)

National Center for Biotechnology Information. PubChem Compound Database; CID=2519, https://pubchem.ncbi.nlm.nih.gov/compound/2519 (accessed Dec 2, 2016)

J.F. Relyea, Radioact. Waste Manage. Nucl. Fuel Cycle 3 (1982) 151

ISO Water quality – Determination of the inhibition of the mobility of Daphnia magna Straus (Cladocera, Crustacea) – Acute toxicity test, 2012

ISO Water quality – Determination of the inhibitory effect of water samples on the light emission of Vibrio fischeri (Luminescent bacteria test) – Part 3: Method using freeze-dried bacteria, 2007

T. Kosjek, H. Andersen, B. Kompare, A. Ledin, E. Heath, Environ. Sci. Technol. 43 (2009) 6256

H. Börnick, P. Eppinger, T. Grischek, E. Worch, Water Res. 35 (2001) 619

H. O. Sun, Y. Du, Z. Y. Zhang, W. J. Jiang, Y. M. Guo, X. W. Lu, Y. M. Zhang., L. W. Sun, Int. J. Environ. Res. Public Health 13 (2016) article No. 925

H. Liu, P. Sun, S. Yang, L. Wang, Z. Wang, Chem. 135 (2015) 182

K. Fent, P.Y. Kunz, A. Zenker, M. Rapp, Mar. Environ. Res. 69 (2010) S4

A. Sieratowicz, D. Kaiser, M. Behr, M. Oetken, J. Oehlmann J. Environ. Sci. Health, A Tox. Hazard Subst. Environ En. 46 (2011) 1311

Y. Kim, K. Choi, J. Jung, S. Park, P.G. Kim, J. Park, Environ. Int. 33 (3) (2007) 370

J. Chevalier, E. Harscoet, M. Keller, P. Pandard, J. Cachot, M. Grote Environ. Toxicol. Chem. 34 (2015) 1760

G.V. Aguirre-Martínez, M. A. Owuor, C. Garrido-Pérez, M.J. Salamanca, T.A. Del Valls, M.L. Martín-Díaz, Chem. 120 (2015) 75

R. Zhuang, R. Zabar, G. Grbovic, D. Dolenc, J. Yao, T. Tisler, P. Trebse, Acta Chim. Slov. 60 (4) (2013) 826

A. J. M. Santos, S. Margarida, A. S. Miranda, J. C. G. Esteves da Silva, Water Res. 46 (2012) 3167.




DOI: https://doi.org/10.2298/JSC170717105B

Copyright (c) 2017 J. Serb. Chem. Soc.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

IMPACT FACTOR 0.797 (139 of 171 journals)
5 Year Impact Factor 0,923 (134 of 171 journals)