Methyldopa electrochemical sensor based on a glassy carbon electrode modified with Cu/TiO2 nanocomposite

Somayeh Tajik, Hadi Beitollahi, Pourya Biparva


A Cu/TiO2 nanocomposite modified glassy carbon electrode (Cu/TiO2/GCE) was fabricated to detect methyldopa by cyclic voltammetry (CV) and different pulse voltammetry (DPV) methods. Compared with bare GCE, the Cu/TiO2/GCE exhibited excellent electrochemical activity for oxidation of methyldopa. Using DPV technique, the calibration curves for methyldopa was found linear in the concentration range of 0.5 μM–800.0 μM and the detection limit (S/N=3) was calculated to be 0.23 μM. Additionally, the prepared electrochemical sensor of Cu/TiO2/GCE demonstrated a practical feasibility in methyldopa tablets and urine samples analysis.


A Cu/TiO2 nanocomposite modified glassy carbon electrode (Cu/TiO2/GCE) was fabricated to detect methyldopa by cyclic voltammetry (CV) and different pulse voltammetry (DPV) methods. Compared with bare GCE, the Cu/TiO2/GCE exhibited excellent electrochemica

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