Novel silver(I) compounds with 1-adamantanamine

Dejan A. Jeremić, Milena Đorđević, Srđan Miletić, Ljubica Andjelković, Dušan Sladić, Ilija Brčeski

Abstract


In this work, three novel silver(I) complexes with an almost completely rigid and bulky monodentate ligand, 1-adamantanamine, were synthesized. Aliphatic amine, 1-adamantanamine, is the sole electron donor ligand in these complexes. In addition to spectroscopic characterization, the basic biological activities of the new compounds were investigated and their minimum inhibitory concentrations were determined. The antifungal and antibacterial activities indicate that these compounds can be potentially applied as new therapeutics.


Keywords


amantadine; silver(I) complexes; rigid and bulky ligand; NMR spectroscopy; biological activity

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DOI: https://doi.org/10.2298/JSC171114041J

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